THE ROLE OF PSILOCYBIN IN DEPRESSION
A 2021 study conducted at Yale University indicates that psilocybin, a psychedelic compound found in magic mushrooms, has the ability to prompt neural plasticity and remodeling of the neurons in the brain resulting in immediate increase in the number of neural connections in the frontal pyramidal cortical cells in mice.
Pyramidal cells within the frontal cortex are responsible for processing various sensory input associated with thinking and behavior regulation in the brain and are associated with depression. This increase in the spine density and size of the frontal cortical pyramidal cells appears to persist for at least one month and was shown to decrease stress-related behavioral deficits in mice.
This remodeling of the frontal pyramidal cells may be the underlying mechanism that explains psilocybin antidepressant effect.
UHSA PARTNERS WITH REVIVE TO STUDY THE ROLE OF PSILOCYBIN
The University of Health Sciences Antigua recently formed a collaboration with Revive Therapeutics of Canada to study the impact of psilocybin and other psychedelic medications on the treatment mental health disorders.
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